Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies - Property and Equipment Useful Life (Detail)

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Summary of Significant Accounting Policies - Property and Equipment Useful Life (Detail)
 12 Months Ended
Dec. 31, 2015
Leasehold Improvements [Member]  
Property, Plant and Equipment [Line Items]  
Property, plant and equipment, estimated Lives shorter of useful life or remaining life of the lease
Laboratory Equipment [Member] | Minimum [Member]  
Property, Plant and Equipment [Line Items]  
Property, plant and equipment, estimated Lives 1 year
Laboratory Equipment [Member] | Maximum [Member]  
Property, Plant and Equipment [Line Items]  
Property, plant and equipment, estimated Lives 14 years
Office and Computer Equipment [Member] | Minimum [Member]  
Property, Plant and Equipment [Line Items]  
Property, plant and equipment, estimated Lives 1 year
Office and Computer Equipment [Member] | Maximum [Member]  
Property, Plant and Equipment [Line Items]  
Property, plant and equipment, estimated Lives 15 years