Quarterly report pursuant to Section 13 or 15(d)

Accrued Expenses - Schedule of Accrued Expenses (Detail)

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Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($)
Mar. 31, 2017
Dec. 31, 2016
Accrued expenses    
Accrued compensation expense $ 844,786 $ 1,198,448
Accrued professional fees, and other 782,203 867,969
Accrued R&D fees 777,573 1,040,321
Accrued audit and tax fees 374,548 454,931
Accrued other 179,767 157,788
Total accrued expenses $ 2,958,877 $ 3,719,457