Annual report pursuant to Section 13 and 15(d)

Property and Equipment, Net - Summary of Property and Equipment (Details)

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Property and Equipment, Net - Summary of Property and Equipment (Details) - USD ($)
$ in Thousands
Dec. 31, 2017
Dec. 31, 2016
Property, Plant and Equipment [Line Items]    
Property and equipment at cost $ 6,913 $ 4,689
Accumulated depreciation (2,879) (2,425)
Property and equipment, net 4,034 2,264
Laboratory equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment at cost 6,101 3,869
Office and computer equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment at cost 494 499
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Property and equipment at cost $ 318 $ 321