Annual report pursuant to Section 13 and 15(d)


Cover - USD ($)
12 Months Ended
Dec. 31, 2020
Mar. 29, 2021
Jun. 30, 2020
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2020    
Current Fiscal Year End Date --12-31    
Document Transition Report false    
Entity File Number 001-37471    
Entity Registrant Name PIERIS PHARMACEUTICALS, INC.    
Entity Incorporation, State or Country Code NV    
Entity Tax Identification Number 30-0784346    
Entity Address, Address Line One 255 State Street    
Entity Address, Address Line Two 9th Floor    
Entity Address, City or Town Boston    
Entity Address, State or Province MA    
Entity Address, Country US    
Entity Address, Postal Zip Code 2109    
City Area Code 857    
Local Phone Number 246-8998    
Title of 12(b) Security Common Stock, par value $0.001 per share    
Trading Symbol PIRS    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Entity Shell Company false    
Entity Public Float     $ 117,421,871
Entity Common Stock, Shares Outstanding   59,718,989  
Documents Incorporated by Reference Certain information required in Part III of this Annual Report on Form 10-K is incorporated from the Registrant’s Proxy Statement for the 2021 Annual Meeting of Stockholders to be filed with the Securities and Exchange Commission.    
Amendment Flag false    
Document Fiscal Year Focus 2020    
Document Fiscal Period Focus FY    
Entity Central Index Key 0001583648