Quarterly report pursuant to Section 13 or 15(d)

Property and Equipment, Net - Summary (Details)

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Property and Equipment, Net - Summary (Details) - USD ($)
$ in Thousands
Mar. 31, 2019
Dec. 31, 2018
Property, Plant and Equipment [Line Items]    
Property and equipment at cost $ 8,170 $ 8,415
Accumulated depreciation (3,277) (3,366)
Property and equipment, net 4,893 5,049
Laboratory equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment at cost 7,165 7,431
Office and computer equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment at cost 683 661
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Property and equipment at cost $ 322 $ 323